This issue happens out of GameEX, and I don't think my images are faulty because they worked before and I never had issues with CD audio.
Anyway, I haven't touched my HTPC/GameEX machine in almost a month and other than updating the Virtual Drive Loader plugin and GameEX I now have a problem not related to either. The CD audio in Kega Fusion is VERY scratchy and it skips when I play a Sega CD ISO - they are in various formats such as .CCD and bin/cue. I don't have any ISO/MP3 rips if that helps any. Now, if I run a REAL Sega CD game via my optical drive, the CD audio works perfectly fine - I tested this with a retail Sonic CD (Japan). Although not being touched in a month, no settings were changed. I get the problem if I manually run Kega Fusion and load the ISO via Daemon Tools - GameEX doesn't make it any better or worse.
Thankfully, other disc based systems are NOT affected - ePSXe and SSF don't give me issues if I run them with or without GameEX.
I've deleted and re-installed Kega Fusion and it doesn't help any, I deleted my SCSI virtual drive and re-added it but again no dice.
Anyone have this issue before?